Identification of the Vulnerable Plaque

• Who is at risk for plaque rupture?

  • Up to 60% of MIs occur in non-obstructive lesions

    • Means no symptoms, negative stress tests

• Identification is Difficult

  • ?EBCT
  • Inflammatory Markers

    • Plaque Temperature, CRP
  • MRI/IVUS
  • Angiography is limited by lumenography

    • Remodeling

• Treatment

  • Aggressive risk factor modification
  • Anything else??

Lipid Core

Thin

Fibrous

Cap

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